Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155272 | 0.78 | CRHBP (0.48) | CRHBPCRHR2DRD2DRD4LMNA | |
| SCHEMBL3524505 | 0.77 | ROCK1 (0.39) | DRD2DRD4LMNAROCK1NOTUM | |
| SCHEMBL3524502 | 0.77 | ROCK1 (0.39) | DRD2DRD4LMNAROCK1NOTUM | |
| SCHEMBL3524506 | 0.77 | ROCK1 (0.39) | DRD2DRD4LMNAROCK1NOTUM | |
| SCHEMBL9073520 | 0.76 | AMPD2 (0.49) | CRHBPCRHR2DRD2DRD4LMNA | |
| SCHEMBL11428861 | 0.74 | CRHBP (0.45) | CRHBPCRHR2DRD2DRD4LMNA | |
| SCHEMBL3975558 | 0.74 | CRHBP (0.47) | CRHBPCRHR2DRD2DRD4LMNA | |
| SCHEMBL8942349 | 0.73 | CRHBP (0.47) | CRHBPCRHR2DRD2DRD4LMNA | |
| SCHEMBL11431643 | 0.73 | CRHBP (0.44) | CRHBPCRHR2DRD2DRD4LMNA | |
| SCHEMBL11419734 | 0.73 | CRHBP (0.47) | CRHBPCRHR2DRD2DRD4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4962200-A | PREVENTS HARDENING OF BLOOD VESSELS BY CONTROLLING FORMATION OF PEROXIDE LIPIDS IN CELL MEMBRANES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0289365-A2 | Novel nitrogen-containing compound | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |