Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15841547 | 0.78 | GFER (0.60) | HSD11B1GFERALDH1A1ABATMAPT | |
| SCHEMBL15841548 | 0.78 | GFER (0.60) | HSD11B1GFERALDH1A1ABATMAPT | |
| SCHEMBL27360882 | 0.75 | GFER (0.53) | HSD11B1GFERALDH1A1ABATMAPT | |
| SCHEMBL8103610 | 0.74 | HSD11B1 (1.00) | HSD11B1GFERSOAT1POLBKCNH2 | |
| SCHEMBL29975007 | 0.72 | L3MBTL1 (0.56) | HSD11B1GFERALDH1A1ABATMAPT | |
| SCHEMBL1997854 | 0.72 | L3MBTL1 (0.56) | HSD11B1GFERALDH1A1ABATMAPT | |
| SCHEMBL31409141 | 0.72 | ALDH1A1 (0.55) | HSD11B1GFERALDH1A1ABATMAPT | |
| SCHEMBL2800404 | 0.70 | ESR1 (0.63) | HSD11B1GFERALDH1A1MAPTPOLB | |
| SCHEMBL9730354 | 0.69 | HSD11B1 (0.49) | HSD11B1GFERALDH1A1MAPTMEN1 | |
| SCHEMBL19850690 | 0.69 | HSD11B1 (0.60) | HSD11B1GFERALDH1A1MAPTSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963691-A | Spirodilactam derivatives | SHELL OIL COMPANY (US) | 1990-10-16 | — | — | US | disclosed |