Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482302 | 0.86 | KEAP1 (0.54) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9517618 | 0.83 | KEAP1 (0.50) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL235080 | 0.79 | KDM4E (0.65) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11856358 | 0.76 | KDM4E (0.70) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10913328 | 0.76 | KDM4E (0.70) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3481711 | 0.76 | KEAP1 (0.52) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9520262 | 0.76 | KEAP1 (0.52) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL40041 | 0.72 | — | — | |
| SCHEMBL12802541 | 0.71 | TDP1 (0.44) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14385507 | 0.71 | KDM4E (0.56) | KDM4EKEAP1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927750-A | SEPARATION AND PURIFICATION OF BIOLOGICAL CELLS USING A COLLOIDAL SILICA, ORGANOSILANE REAGENT | Simpson, Jeanette (US) | 1990-05-22 | — | — | US | disclosed |