Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482302 | 0.92 | KEAP1 (0.54) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL10411809 | 0.83 | KDM4E (0.46) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL7103406 | 0.82 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3GAA | |
| SCHEMBL11609926 | 0.82 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3GAA | |
| SCHEMBL16173592 | 0.82 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3GAA | |
| SCHEMBL9738476 | 0.82 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3GAA | |
| SCHEMBL9740021 | 0.82 | KEAP1 (0.68) | KEAP1SMN1; SMN2HPGDDUSP3GAA | |
| SCHEMBL7239607 | 0.80 | KEAP1 (0.71) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL3481711 | 0.78 | KEAP1 (0.52) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL9520262 | 0.78 | KEAP1 (0.52) | KEAP1SMN1; SMN2HPGDDUSP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417755-B1 | Packing for chromatography and its use for separating water soluble organic compounds | DAISO CO LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5103000-A | PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME | DAISO CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0417755-A1 | Packing for chromatography and its use for separating water soluble organic compounds | DAISO CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |