Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481711 | 0.88 | KEAP1 (0.52) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL3482302 | 0.85 | KEAP1 (0.54) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL13532385 | 0.83 | KEAP1 (0.56) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL9516675 | 0.81 | HRH3 (0.52) | SMN1; SMN2SIGMAR1MAPK1CYP1A2KCNH2 | |
| SCHEMBL31550574 | 0.79 | KEAP1 (0.52) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL11647717 | 0.79 | KEAP1 (0.52) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL3481792 | 0.79 | KEAP1 (0.52) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL9518402 | 0.78 | CXCR4 (0.47) | SMN1; SMN2SIGMAR1CYP1A2CHRM2CHRM1 | |
| SCHEMBL29113359 | 0.78 | KEAP1 (0.50) | KEAP1SMN1; SMN2HPGDDUSP3LMNA | |
| SCHEMBL9517618 | 0.78 | KEAP1 (0.50) | KEAP1SMN1; SMN2HPGDDUSP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417755-B1 | Packing for chromatography and its use for separating water soluble organic compounds | DAISO CO LTD (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-5103000-A | PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME | DAISO CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0417755-A1 | Packing for chromatography and its use for separating water soluble organic compounds | DAISO CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |