Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413895 | 0.93 | LMNA (0.49) | LMNAHPGDUSP2HTTCYP2C9 | |
| SCHEMBL10413903 | 0.85 | KDM4E (0.41) | LMNAHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10414001 | 0.82 | KDM4E (0.46) | LMNAHPGDUSP2HTTALDH1A1 | |
| SCHEMBL10413898 | 0.80 | ADRB2 (0.44) | LMNAHPGDUSP2HTTALDH1A1 | |
| SCHEMBL10413303 | 0.78 | KMT2A (0.44) | LMNAHPGDUSP2HTTALDH1A1 | |
| SCHEMBL10413402 | 0.76 | HSD17B10 (0.56) | LMNAHPGDHTTALDH1A1KDM4E | |
| SCHEMBL28530121 | 0.72 | LMNA (0.80) | LMNAHPGDHTTCYP2C9ATP6V1B2 | |
| SCHEMBL10413375 | 0.72 | SMN1; SMN2 (0.49) | LMNAHPGDCYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL10414003 | 0.72 | LMNA (0.61) | LMNAHPGDUSP2HTTCYP2C9 | |
| SCHEMBL11286741 | 0.69 | ALDH1A1 (0.53) | LMNAHPGDHTTCYP2C9ATP6V1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |