Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412667 | 0.93 | LMNA (0.49) | LMNAHPGDHTTUSP2ALDH1A1 | |
| SCHEMBL10413898 | 0.87 | ADRB2 (0.44) | LMNAHPGDHTTUSP2ALDH1A1 | |
| SCHEMBL10413303 | 0.85 | KMT2A (0.44) | LMNAHPGDHTTUSP2ALDH1A1 | |
| SCHEMBL10413402 | 0.83 | HSD17B10 (0.56) | LMNAHPGDHTTALDH1A1KDM4E | |
| SCHEMBL10413903 | 0.78 | KDM4E (0.41) | LMNAHPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3977245 | 0.76 | ALDH1A1 (0.53) | LMNAHPGDHTTALDH1A1KDM4E | |
| SCHEMBL10980975 | 0.76 | ALDH1A1 (0.52) | LMNAHPGDHTTALDH1A1KDM4E | |
| SCHEMBL11092618 | 0.75 | LMNA (0.61) | LMNAHPGDHTTALDH1A1KDM4E | |
| SCHEMBL11286741 | 0.75 | ALDH1A1 (0.53) | LMNAHPGDHTTALDH1A1KDM4E | |
| SCHEMBL10414001 | 0.75 | KDM4E (0.46) | LMNAHPGDHTTUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |