Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625378 | 0.86 | GFER (0.39) | SMN1; SMN2MEN1GAAMAPTHTT | |
| SCHEMBL2156631 | 0.85 | S100B (0.60) | MTNR1AMTNR1BSMN1; SMN2MEN1GAA | |
| SCHEMBL244238 | 0.79 | GFER (0.63) | MTNR1AMTNR1BSMN1; SMN2MEN1GAA | |
| SCHEMBL29387324 | 0.79 | GFER (0.63) | MTNR1AMTNR1BSMN1; SMN2MEN1GAA | |
| SCHEMBL10412003 | 0.77 | MAPT (0.54) | SMN1; SMN2MEN1GAAMAPTHTT | |
| SCHEMBL2156595 | 0.77 | ALDH1A1 (0.55) | MTNR1AMTNR1BSMN1; SMN2MEN1GAA | |
| SCHEMBL1432654 | 0.77 | MTNR1A (0.48) | MTNR1AMTNR1BSMN1; SMN2MEN1GAA | |
| SCHEMBL8978503 | 0.76 | MTNR1A (0.68) | MTNR1AMTNR1BSMN1; SMN2MEN1GAA | |
| SCHEMBL4843540 | 0.76 | ALDH1A1 (0.61) | MTNR1AMTNR1BSMN1; SMN2MEN1GAA | |
| SCHEMBL6732179 | 0.76 | S100B (0.53) | SMN1; SMN2MEN1MAPTKMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4912258-A | A 4-fluoroaniline compound | BOEHRINGER MANNHEIM GMBH (DE) | 1990-03-27 | — | — | US | claimed |
| EP-0161482-B1 | FLUORINATED ANILINE DERIVATIVES AND THEIR USE | Roche Diagnostics GmbH (DE) | 1989-09-13 | — | — | EP | claimed |
| EP-0161482-A1 | Fluorinated aniline derivatives and their use | Roche Diagnostics GmbH (DE) | 1985-11-21 | — | — | EP | claimed |
| US-4912258-A | A 4-fluoroaniline compound | BOEHRINGER MANNHEIM GMBH (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0161482-B1 | FLUORINATED ANILINE DERIVATIVES AND THEIR USE | Roche Diagnostics GmbH (DE) | 1989-09-13 | — | — | EP | disclosed |
| EP-0267247-A1 | PROCESS AND REAGENT FOR DETECTING HEART LESIONS OR DISEASES | Roche Diagnostics GmbH (DE) | 1988-05-18 | — | — | EP | disclosed |
| WO-1987006619-A1 | PROCESS AND REAGENT FOR DETECTING HEART LESIONS OR DISEASES | BOEHRINGER MANNHEIM GMBH (DE) | 1987-11-05 | — | — | WO | disclosed |
| EP-0243901-A1 | Process and reagent for the detection of heart lesions or heart diseases | Roche Diagnostics GmbH (DE) | 1987-11-04 | — | — | EP | disclosed |
| EP-0161482-A1 | Fluorinated aniline derivatives and their use | Roche Diagnostics GmbH (DE) | 1985-11-21 | — | — | EP | disclosed |