Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.62 |
| ▸ | TTR | P02766 | 1/20 | 0.62 |
| ▸ | JUN | P05412 | 1/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.62 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10412984 | 1.00 | FOS (0.62) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL4624766 | 0.86 | LDHA (0.57) | CYP3A4ALOX15ALOX12LMNAALDH1A1 | |
| SCHEMBL3388461 | 0.86 | LDHA (0.57) | CYP3A4ALOX15ALOX12LMNAALDH1A1 | |
| SCHEMBL3388456 | 0.86 | LDHA (0.57) | CYP3A4ALOX15ALOX12LMNAALDH1A1 | |
| 3-O-Methyl-Alpha-Methyldopamine SCHEMBL9434236 | 0.81 | FOS (0.75) | FOSTTRJUNNR3C1HSD17B1 | |
| 3-O-Methyl-Alpha-Methyldopamine SCHEMBL28514447 | 0.81 | FOS (0.75) | FOSTTRJUNNR3C1HSD17B1 | |
| 3-O-Methyl-Alpha-Methyldopamine SCHEMBL9434243 | 0.81 | FOS (0.75) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL5311684 | 0.80 | ALOX15 (0.59) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL849960 | 0.80 | ALOX15 (0.59) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL11136069 | 0.80 | ALOX15 (0.59) | FOSTTRJUNNR3C1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4970297-A | CONTAINING ISOXAZOLE RING | SYNTEX (U.S.A.) INC. (US) | 1990-11-13 | — | — | US | disclosed |