Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10652767 | 0.95 | DRD2 (0.48) | MAOBMAOADRD2DRD4DRD3 | |
| SCHEMBL9828847 | 0.93 | HTR1A (0.54) | HTR1A | |
| SCHEMBL11351695 | 0.89 | HTR1A (0.60) | HTR1A | |
| SCHEMBL10648427 | 0.88 | MAOB (0.44) | MAOB | |
| SCHEMBL10647445 | 0.88 | HTR1A (0.52) | HTR1A | |
| SCHEMBL10646279 | 0.88 | MAOB (0.45) | MAOBMAOADRD2DRD4DRD3 | |
| SCHEMBL10414161 | 0.86 | DRD2 (0.47) | MAOBMAOADRD2DRD4DRD3 | |
| SCHEMBL10412923 | 0.85 | SLC18A3 (0.47) | MAOBMAOASLC18A3DRD2DRD4 | |
| SCHEMBL10413623 | 0.85 | HTR1D (0.53) | HTR1A | |
| SCHEMBL10414111 | 0.85 | HTR1A (0.54) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916143-A | Hydroxyindole esters | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | disclosed |