Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10413375 | 0.90 | SMN1; SMN2 (0.49) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL10413973 | 0.87 | LMNA (0.60) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL10412649 | 0.84 | ADRB2 (0.49) | KMT2ASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL3977245 | 0.84 | ALDH1A1 (0.53) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL10414338 | 0.83 | KMT2A (0.48) | KMT2ASMN1; SMN2ALDH1A1TSHRMAPT | |
| SCHEMBL11286741 | 0.83 | ALDH1A1 (0.53) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL11283380 | 0.81 | ALDH1A1 (0.51) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL11346134 | 0.81 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL8941946 | 0.81 | ALDH1A1 (0.55) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 | |
| SCHEMBL9775932 | 0.80 | ALDH1A1 (0.54) | KMT2ASMN1; SMN2ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4945160-A | Preparation of certain 7-substituted quinolones | WARNER-LAMBERT COMPANY (US) | 1990-07-31 | — | — | US | disclosed |