SCHEMBL1041344

SCHEMBL1041344

Fc1ccccc1P(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
NFE2L2 Q16236 5/20 0.36
ALDH1A1 P00352 1/20 0.36
ALOX15 P16050 1/20 0.36
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
IDO1 P14902 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30426297 0.83 ACHE (0.38) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL2154282 0.83 ACHE (0.38) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL1986740 0.78 TSHR (0.35)
SCHEMBL30391714 0.78 TSHR (0.35)
SCHEMBL30700143 0.77 ACHE (0.41) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL476837 0.77 ACHE (0.41) ACHENFE2L2ALDH1A1ALOX15CES2
SCHEMBL29534836 0.75 CYP3A4 (0.36) ACHENFE2L2ALDH1A1ALOX15
SCHEMBL2154086 0.75 CYP3A4 (0.36) ACHENFE2L2ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL11570767 0.74 ACHE (0.39) ACHENFE2L2ALDH1A1ALOX15CES2
Hydrochloric Acid SCHEMBL11570761 0.74 ACHE (0.39) ACHENFE2L2ALDH1A1ALOX15CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116328837-A Ethylene oligomerization catalyst composition and application thereof 中国石油化工股份有限公司 2023-06-27 CN disclosed
CN-116328838-A Metal-organic framework supported ethylene oligomerization catalyst composition and application thereof 中国石油化工股份有限公司 2023-06-27 CN disclosed
CN-116328839-A Supported main catalyst for oligomerization of ethylene, catalyst composition for oligomerization of ethylene and application 中国石油化工股份有限公司 2023-06-27 CN disclosed
CN-116328836-A Porous organic polymer supported ethylene polymerization main catalyst, ethylene polymerization catalyst composition and application 中国石油化工股份有限公司 2023-06-27 CN disclosed
EP-2328905-B2 ETHYLENE TETRAMERIZATION CATALYSTS COMPRISING P-N-P LIGANDS NOVA CHEM INT SA (CH) 2023-05-31 EP disclosed
US-7915455-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-29 US disclosed
EP-2272852-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex Sumitomo Chemical Company, Limited (JP) 2011-01-12 EP disclosed
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED 2009-06-04 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
CN-101157592-A Method for separating acid from chemical reaction mixture by using ionic liquid BASF AG (DE) 2008-04-09 CN disclosed
CN-100349833-C Method for separating acid from chemical reaction mixture by using ionic liquid BASF AG (DE) 2007-11-21 CN disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed
EP-1683802-A1 TRANSITION METAL COMPLEX LIGAND AND OLEFIN POLYMERIZATION CATALYST CONTAINING TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP disclosed
CN-1622925-A Method for separating acid from chemical reaction mixture by using ionic liquid BASF AG (DE) 2005-06-01 CN disclosed
EP-1472201-A2 METHOD FOR THE SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC FLUIDS BASF AKTIENGESELLSCHAFT (DE) 2004-11-03 EP disclosed
EP-1470136-A1 METHOD FOR THE SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC FLUIDS BASF AKTIENGESELLSCHAFT (DE) 2004-10-27 EP disclosed
WO-2003062171-A2 METHOD FOR THE SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC FLUIDS BASF AKTIENGESELLSCHAFT (DE) 2003-07-31 WO disclosed
WO-2003062251-A1 METHOD FOR THE SEPARATION OF ACIDS FROM CHEMICAL REACTION MIXTURES BY MEANS OF IONIC FLUIDS BASF AKTIENGESELLSCHAFT (DE) 2003-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 ACHE 4428/4885NFE2L2 198/4885ALDH1A1 4017/4885
US-20090143620-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 ACHE 4428/4885NFE2L2 198/4885ALDH1A1 4017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.