SCHEMBL476837

SCHEMBL476837

Fc1ccccc1P(c1ccccc1F)c1ccccc1F

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.41
NFE2L2 Q16236 4/20 0.39
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
TAAR1 Q96RJ0 1/20 0.35
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
IDO1 P14902 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
KDM1A O60341 1/20 0.31
KDM1B Q8NB78 1/20 0.31
MGLL Q99685 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30700143 1.00 ACHE (0.41) ACHENFE2L2CES2CES1TAAR1
Hydrochloric Acid SCHEMBL11570761 0.97 ACHE (0.39) ACHENFE2L2CES2CES1TAAR1
Hydrochloric Acid SCHEMBL11570767 0.97 ACHE (0.39) ACHENFE2L2CES2CES1TAAR1
SCHEMBL29005861 0.84 CYP3A4 (0.52) ACHENFE2L2CES2CES1TAAR1
SCHEMBL10797329 0.84 CYP3A4 (0.52) ACHENFE2L2CES2CES1TAAR1
SCHEMBL16460568 0.83 ALDH1A1 (0.34) CES2CES1ALDH1A1CYP3A4TDP1
SCHEMBL1041344 0.77 ACHE (0.38) ACHENFE2L2CES2CES1TAAR1
SCHEMBL2154211 0.77 CES2 (0.39) ACHENFE2L2CES2CES1TAAR1
SCHEMBL19968527 0.77 ACHE (0.38) ACHENFE2L2CES2CES1TAAR1
SCHEMBL12620592 0.77 CES2 (0.39) ACHENFE2L2CES2CES1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118388585-A Preparation method of amide and ester compounds based on visible light catalysis 泰山学院 2024-07-26 CN claimed
CN-114478627-A Allylation monophosphine ligand and preparation method thereof 湖北大学 2022-05-13 CN claimed
CN-110003231-B 1, 1-spironorbornane-pyrano [4, 3-b ] chromone compound and preparation method and application thereof 遵义医科大学 2021-08-10 CN claimed
CN-109851635-B Novel alkylated monophosphine ligand and simple preparation method thereof 湖北大学 2021-03-16 CN claimed
EP-4174047-B1 METHOD FOR PRODUCING CYCLIC OLEFIN COMPOUND MITSUI CHEMICALS INC (JP) 2026-05-13 EP disclosed
CN-115298163-B Preparation of aromatic carboxamides by palladium catalyzed carbonylation 巴斯夫欧洲公司 2024-11-19 CN disclosed
CN-118388585-A Preparation method of amide and ester compounds based on visible light catalysis 泰山学院 2024-07-26 CN disclosed
WO-2024127999-A1 METHOD FOR PRODUCING CYCLIC OLEFIN COMPOUND 三井化学株式会社 2024-06-20 WO disclosed
US-11987538-B2 Method for producing cyclic olefin compound MITSUI CHEMICALS, INC. (JP) 2024-05-21 US disclosed
CN-114989000-B Process for preparing unsaturated carboxylic acids by carbonylation of allyl alcohol and its acylated products 巴斯夫欧洲公司 2024-05-10 CN disclosed
EP-4101892-B1 COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, THERMALLY CONDUCTIVE SHEET, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORP (JP) 2024-02-21 EP disclosed
US-20230219868-A1 METHOD FOR PRODUCING CYCLIC OLEFIN COMPOUND MITSUI CHEMICALS, INC. (JP) 2023-07-13 US disclosed
WO-2004035636-A2 POLYMERIZED CYCLOOLEFINS USING TRANSITION METAL CATALYST AND END PRODUCTS THEREOF PROMERUS, LLC (US) 2004-04-29 WO disclosed
US-6187890-B1 CROSSLINK BY REACTION OF ALIPHATICALLY UNSATURATED GROUPS WITH SI-BONDED HYDROGEN (HYDROSILYLATION) IN THE PRESENCE OF A CATALYST, TYPICALLY A PLATINUM COMPOUND WACKER-CHEMIE GMBH (DE) 2001-02-13 US disclosed
EP-0322811-B1 Process for producing aldehydes or mixtures of ketones and aldehydes UNION CARBIDE CORP (US) 1993-11-10 EP disclosed
US-4945185-A HYDROCARBONYLATION UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-07-31 US disclosed
EP-0219906-B1 PROCESS FOR THE PREPARATION OF ALKYLIDENE DIESTERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-06-06 EP disclosed
EP-0322811-A2 Process for producing aldehydes or mixtures of ketones and aldehydes UNION CARBIDE CORPORATION (US) 1989-07-05 EP disclosed
EP-0219906-A2 Process for the preparation of alkylidene diesters SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-04-29 EP disclosed
US-4661623-A CATALYST SELECTIVITY ASHLAND OIL, INC. (US) 1987-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11987538-B2 Method for producing cyclic olefin compound ODC1, ME1, AOC1 ACHE 4177/4885NFE2L2 312/4885CES2 3223/4885
US-20230219868-A1 METHOD FOR PRODUCING CYCLIC OLEFIN COMPOUND ODC1, ME1, AOC1 ACHE 4326/4885NFE2L2 368/4885CES2 3245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.