SCHEMBL104173

SCHEMBL104173

O=Cc1cccc(Br)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29792032 1.00
Pyrimidine SCHEMBL29174127 0.88 TERT (0.39)
SCHEMBL303150 0.82 CCR1 (0.55)
SCHEMBL6629191 0.81 STAT3 (0.38)
SCHEMBL840645 0.79 ALDH1A1 (0.39)
SCHEMBL840646 0.79 ALDH1A1 (0.39)
SCHEMBL25400847 0.76
SCHEMBL805887 0.76
SCHEMBL8772140 0.76 USP9X (0.35)
SCHEMBL8892427 0.76 USP9X (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2030 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535445-B Chiral oxazoline pyridine-cobalt compound and synthetic method and application thereof 郑州大学 2025-05-13 CN claimed
CN-116410126-B Ligand, ruthenium complex, preparation method thereof and application of ligand and ruthenium complex in catalyzing alkyne semi-hydrogenation reaction 河北师范大学 2025-05-09 CN claimed
CN-118878562-B Anilino pyridine amino-zinc catalyst and preparation method and application thereof 天津大学 2025-04-18 CN claimed
CN-115382580-B Heterogeneous platinum catalyst and application thereof in synthesis of gamma-chloropropyl trichlorosilane 青岛科技大学 2025-04-11 CN claimed
CN-115318342-B Heterogeneous bimetallic platinum catalyst and application thereof in synthesis of gamma-chloropropyl trichlorosilane 青岛科技大学 2025-03-28 CN claimed
CN-118878562-A Anilino pyridine amino-zinc catalyst and preparation method and application thereof 天津大学 2024-11-01 CN claimed
CN-118878459-A Anilino pyridine amino-aluminum catalyst and preparation method and application thereof 天津大学 2024-11-01 CN claimed
CN-116332964-B Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound 西北大学 2024-05-24 CN claimed
CN-117700434-A Tetranuclear node Zn (II) complex with anti-tumor activity and preparation method and application thereof 河南中医药大学 2024-03-15 CN claimed
CN-116535445-A Chiral oxazoline pyridine-cobalt compound and synthetic method and application thereof 郑州大学 2023-08-04 CN claimed
CN-103724251-B STAT3 (Signal Transducer and Activator of Transcription 3)-targeting small molecular compound as well as preparation method and application thereof UNIV FUZHOU 2015-07-22 CN claimed
CN-103613479-B Preparation method of aromatic carboxylic acid compound UNIV DALIAN TECH 2015-04-08 CN claimed
CN-103613479-A Preparation method of aromatic carboxylic acid compound UNIV DALIAN TECH 2014-03-05 CN claimed
CN-103360303-A Compound with pyridine as nucleus, preparation method and applications UNIV SOUTH CHINA TECH 2013-10-23 CN claimed
CN-101367891-B Nitrogen-nitrogen-oxygen nickel complex catalytic system for addition polymerisation of norbornene and its derivant, preparation method and uses thereof UNIV SOUTH CENTRAL NATIONALITI 2010-09-08 CN claimed
EP-1253152-B1 METHOD OF CONVERTING FUNCTIONAL GROUP THROUGH HALOGEN-METAL EXCHANGE REACTION BANYU PHARMA CO LTD (JP) 2009-11-04 EP claimed
CN-101367891-A Nitrogen-nitrogen-oxygen nickel complex catalytic system for addition polymerisation of norbornene and its derivant, preparation method and uses thereof SOUTH CENTRAL UNIVERSITY FOR N (CN) 2009-02-18 CN claimed
US-6946559-B2 Replacing a halogen atom with an electrophilic group (e.g., a formyl group) using either a mixture of an organomagnesium halide and an alkyllithium or a reaction product of the two, such as trialkylmagnesium lithium BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-09-20 US claimed
US-20030130511-A1 Method of converting functional group through halogen-metal exchange reaction MSD K.K. (JP) 2003-07-10 US claimed
EP-1253152-A1 METHOD OF CONVERTING FUNCTIONAL GROUP THROUGH HALOGEN-METAL EXCHANGE REACTION BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-10-30 EP claimed