Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420218 | 0.99 | MEN1 (0.52) | MEN1KMT2AMAPTTP53CRHBP | |
| SCHEMBL10419451 | 0.88 | MMP2 (0.55) | MEN1KMT2AMAPTTP53L3MBTL1 | |
| SCHEMBL10419485 | 0.87 | MMP9 (0.54) | MEN1KMT2AMAPTTP53L3MBTL1 | |
| SCHEMBL10502883 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2AMAPTMMP9MMP2 | |
| SCHEMBL10420389 | 0.84 | LMNA (0.47) | MEN1KMT2AMAPTMMP9MMP2 | |
| SCHEMBL10419455 | 0.84 | LMNA (0.47) | MEN1KMT2AMAPTMMP9MMP2 | |
| SCHEMBL10419276 | 0.84 | ALDH1A1 (0.48) | MEN1KMT2AMAPTMMP9MMP2 | |
| SCHEMBL9614247 | 0.82 | MMP9 (0.46) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL6932071 | 0.82 | TDP1 (0.53) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL9614130 | 0.81 | MMP9 (0.48) | MEN1KMT2AMAPTL3MBTL1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933367-A | Carboxylic acid derivatives, processes for the preparation thereof, the use thereof, and pharmaceutical compositions which contain these compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0226636-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR MANUFACTURING PROCESS, USE AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1989-02-08 | — | — | EP | disclosed |