Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzoyl Formic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 14/20 | 0.65 |
| ▸ | CES1 | P23141 | 13/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoyl Formic Acid SCHEMBL1702148 | 0.97 | CES2 (0.68) | CES2CES1CA2CA4TSHR | |
| Benzoyl Formic Acid SCHEMBL1446195 | 0.95 | CES2 (0.65) | CES2CES1CA2CA4TSHR | |
| Benzoyl Formic Acid SCHEMBL8623983 | 0.95 | CES2 (0.65) | CES2CES1CA2CA4TSHR | |
| Benzoyl Formic Acid SCHEMBL3079821 | 0.95 | CES2 (0.65) | CES2CES1CA2CA4TSHR | |
| Benzoyl Formic Acid SCHEMBL5448316 | 0.95 | CES2 (0.65) | CES2CES1CA2CA4TSHR | |
| Benzoyl Formic Acid SCHEMBL1532670 | 0.95 | CES2 (0.65) | CES2CES1CA2CA4TSHR | |
| Benzoyl Formic Acid SCHEMBL699116 | 0.84 | CES2 (0.52) | CES2CES1CA2CA4TSHR | |
| Benzil SCHEMBL7142843 | 0.80 | CES2 (1.00) | CES2CES1CA2CA4TSHR | |
| Benzil SCHEMBL66 | 0.80 | CES2 (1.00) | CES2CES1CA2CA4TSHR | |
| Benzil SCHEMBL9517636 | 0.80 | CES2 (1.00) | CES2CES1CA2CA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853290-B2 | Photosensitive composition | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2014-10-07 | — | — | US | disclosed |
| EP-2270114-B1 | PHOTOBASE GENERATOR | SAN APRO LTD (JP) | 2014-07-09 | — | — | EP | disclosed |
| US-20140045966-A1 | PHOTOSENSITIVE COMPOSITION. CURED ARTICLE, AND METHOD FOR PRODUCING ACTINICALLY CURED ARTICLE | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2014-02-13 | — | — | US | disclosed |
| US-8329771-B2 | Photobase generator | SAN-APRO LIMITED (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20120142806-A1 | PHOTOSENSITIVE COMPOSITION | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2441778-A1 | PHOTOSENSITIVE COMPOSITION | Sanyo Chemical Industries, Ltd. (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-20110028585-A1 | PHOTOBASE GENERATOR | SAN-APRO LIMITED (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-2270114-A1 | PHOTOBASE GENERATOR | San-Apro Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028585-A1 | PHOTOBASE GENERATOR | CCKBR, XDH, PPOX | CES2 1298/4885CES1 1946/4885CA2 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.