SCHEMBL10423950

SCHEMBL10423950

O=S(=O)(O)c1cc(S(=O)(=O)O)c2[nH]nnc2c1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.36
FYN P06241 1/20 0.36
ING2 Q9H160 1/20 0.32
ALDH1A1 P00352 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
CASP6 P55212 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6051976 0.80 LCK (0.42) LCKFYNALDH1A1HSD17B10
SCHEMBL9172856 0.79 LCK (0.41) LCKFYNALDH1A1HSD17B10
SCHEMBL1485877 0.79 CASP6 (0.35) LCKFYNALDH1A1CYP2C9CYP2C19
SCHEMBL1485803 0.77 SUMO2 (0.41) LCKFYNALDH1A1CYP2C9CYP2C19
SCHEMBL11407010 0.75 ALDH1A1 (0.38) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10
SCHEMBL338619 0.72 CYP2C19 (0.36) LCKFYNING2ALDH1A1CYP2C9
SCHEMBL1485996 0.72 MPL (0.40) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10
SCHEMBL2443793 0.71 LCK (0.32) LCKFYNING2
SCHEMBL1156233 0.70 HDAC6 (0.41) LCKFYNALDH1A1CYP2C9CYP2C19
SCHEMBL1485928 0.70 CASP6 (0.45) ALDH1A1CYP2C9CYP2C19CASP6HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4904564-A PHENOLIC-FORMALDEHYDE NOVOLAK; DIAZO SENSITIZER; IMIDAZOLE, BENZIMIDAZOLE, TRIAZOLE OR INDAZOLE TO INCREASE SOLUBILITY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1990-02-27 US disclosed
EP-0346650-A2 Process for imaging multi-layer resist structure International Business Machines Corporation (US) 1989-12-20 EP disclosed
EP-0139090-B1 PROCESS FOR THE PRE-TREATMENT OF POLYIMIDES SCHERING AKTIENGESELLSCHAFT (DE) 1988-07-27 EP disclosed
US-4517254-A ALKALI METAL HYDROXIDE, AMINOALKYLPOLYACID COMPOUNT SCHERING AKTIENGESELLSCHAFT (DE) 1985-05-14 US disclosed
EP-0139090-A1 Process for the pre-treatment of polyimides SCHERING AKTIENGESELLSCHAFT (DE) 1985-05-02 EP disclosed
US-4248632-A ACTIVATION OF A POLYMER SURFACE WITH A PALLADIUM COMPLEX SALT SCHERING AKTIENGESELLSCHAFT (DE) 1981-02-03 US disclosed