SCHEMBL2443793

SCHEMBL2443793

O=S(=O)(O)c1cc(S(=O)(=O)O)c2[nH][c]nc2c1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
ING2 Q9H160 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27724917 0.98 LCK (0.31) LCKFYNING2
SCHEMBL6370889 0.71 HDAC6 (0.40)
SCHEMBL338619 0.71 CYP2C19 (0.36) LCKFYNING2
SCHEMBL10423950 0.71 LCK (0.36) LCKFYNING2
SCHEMBL17926194 0.67 ALDH1A1 (0.42) LCKFYNING2
Bisdisulizole SCHEMBL7707182 0.67 HDAC6 (0.49)
Bisdisulizole SCHEMBL7706777 0.67 HDAC6 (0.49)
SCHEMBL5420687 0.63 LCK (0.44) LCKFYNING2
SCHEMBL3495112 0.63 ING2 (0.54) LCKFYNING2
SCHEMBL3899723 0.63 ALDH1A1 (0.48) LCKFYNING2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8821842-B2 Isoalkane mixture, its preparation and use BASF SE (DE) 2014-09-02 US disclosed
WO-2011107411-A1 PYRANOPYRANONE DERIVATIVES AS ANTIMICROBIAL AGENTS BASF SE (DE) 2011-09-09 WO disclosed
US-20090258041-A1 Protection of Oxidizable Agents CIBA CORP. 2009-10-15 US disclosed
US-20090092642-A1 Skin and/or Hair Products, Containing Compounds With an Isoprenoid Structure BEIERSDORF AG (DE) 2009-04-09 US disclosed
CN-101282765-A Use of polyisobutenyl succinic anhydride-based block copolymers in cosmetic preparations BASF AG (DE) 2008-10-08 CN disclosed
US-20080193404-A1 Cosmetic; free from intrinsic odors and have an extremely wide liquid interval; heat transfer liquid; fuel additives and low-temperature fuel; shock absorber oil BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US disclosed
US-20080182808-A1 OLIGORIBONUCLEOTIDES FOR THE TREATMENT OF DEGENERATIVE SKIN CONDITIONS BY RNA INTERFERENCE BEIERSDORF, INC. 2008-07-31 US disclosed
US-20070243147-A1 Skin and/or Hair Composition Containing Compounds for Increasing The Tanning of Skin BEIERSDORF AG (DE) 2007-10-18 US disclosed
US-7270804-B2 Use of one or several substances selected from the group of pyrimidines and purines in cosmetic preparations for tanning the skin BEIERSDORF AG (DE) 2007-09-18 US disclosed
US-20070189984-A1 Agents for use on skin and/or hair containing quadruply substituted cyclohexene compounds BEIERSDORF AF, (DE) 2007-08-16 US disclosed
US-20070041925-A1 Skin and hair care preparation containing a combination of protein hydrolyzates BEIERSDORF AG (DE) 2007-02-22 US disclosed
US-20060093633-A1 Cosmetic and/or dermatological preparation comprising 2,3-dibenzylbutyrolactones BEIERSDORF AG (DE) 2006-05-04 US disclosed
US-20060018869-A1 Cosmetic or dermatological preparation with a content of creatine, creatinine or derivatives thereof in combination with soybean germ extract BEIERSDORF AG 2006-01-26 US disclosed
US-20060008440-A1 Cosmetic or dermatological preparations having a content of anti-freezing proteins and/or anti-freezing glycoproteins BEIERSDORF AG (DE) 2006-01-12 US disclosed
US-20050276764-A1 Topical use of bis-arylimidazo[1,2-a]thiolane derivatives BEIERSDORF AG 2005-12-15 US disclosed
US-20050261222-A1 Oligoribonucleotides for the treatment of irritative or inflammatory skin symptoms through RNA interference BEIERSDORF AG 2005-11-24 US disclosed
US-20050031572-A1 Cosmetic or dermatological preparations including hops or hop-malt extracts and methods of using same for the prophylaxis and treatment of skin symptoms BEIERSDORF AG 2005-02-10 US disclosed
US-20050019279-A1 Cosmetic or dermatological preparation containing an octadecene dioic acid and a UV filtering substance BEIERSDORF AG 2005-01-27 US disclosed
US-20050002880-A1 Cosmetic or dermatological preparations containing one or more ketohexoses BEIERSDORF AG. (DE) 2005-01-06 US disclosed
CN-1535676-A Face-beautifying/or skin-care composition 拜埃尔斯多尔夫股份公司 2004-10-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070189984-A1 Agents for use on skin and/or hair containing quadruply substituted cyclohexene compounds TYR, MC1R, MITF LCK 2180/4885FYN 3635/4885ING2 2534/4885
US-20050019279-A1 Cosmetic or dermatological preparation containing an octadecene dioic acid and a UV filtering substance MC1R, CUTA, DOHH LCK 3461/4885FYN 3280/4885ING2 4210/4885
US-20050002880-A1 Cosmetic or dermatological preparations containing one or more ketohexoses CUTA, TREH, KHK LCK 1166/4885FYN 2901/4885ING2 4859/4885
US-20080182808-A1 OLIGORIBONUCLEOTIDES FOR THE TREATMENT OF DEGENERATIVE SKIN CONDITIONS BY RNA INTERFERENCE DCLRE1B, POLR1C, POLRMT LCK 2785/4885FYN 3180/4885ING2 2473/4885
US-20080193404-A1 Cosmetic; free from intrinsic odors and have an extremely wide liquid interval; heat transfer liquid; fuel additives and low-temperature fuel; shock absorber oil CUTA, TRPA1, FDFT1 LCK 1270/4885FYN 2192/4885ING2 1146/4885
US-20070243147-A1 Skin and/or Hair Composition Containing Compounds for Increasing The Tanning of Skin TYR, MC1R, CUTA LCK 2378/4885FYN 2825/4885ING2 2525/4885
US-20060008440-A1 Cosmetic or dermatological preparations having a content of anti-freezing proteins and/or anti-freezing glycoproteins CUTA, SSB, SERPINA6 LCK 2736/4885FYN 2508/4885ING2 3976/4885
US-20090258041-A1 Protection of Oxidizable Agents LPO, TYR, HAO2 LCK 4552/4885FYN 4524/4885ING2 1886/4885
US-20060093633-A1 Cosmetic and/or dermatological preparation comprising 2,3-dibenzylbutyrolactones DPM1, TYR, DSG1 LCK 696/4885FYN 1148/4885ING2 3840/4885
US-20050276764-A1 Topical use of bis-arylimidazo[1,2-a]thiolane derivatives ITCH, TRPA1, TPH1 LCK 2189/4885FYN 4510/4885ING2 1851/4885
US-20090092642-A1 Skin and/or Hair Products, Containing Compounds With an Isoprenoid Structure SRD5A2, SRD5A1, CUTA LCK 1558/4885FYN 653/4885ING2 1789/4885
US-20060018869-A1 Cosmetic or dermatological preparation with a content of creatine, creatinine or derivatives thereof in combination with soybean germ extract CKMT1A; CKMT1B, AGER, CUTA LCK 1901/4885FYN 3849/4885ING2 4002/4885
US-20050031572-A1 Cosmetic or dermatological preparations including hops or hop-malt extracts and methods of using same for the prophylaxis and treatment of skin symptoms CUTA, TYR, HMBS LCK 331/4885FYN 857/4885ING2 975/4885
US-20050261222-A1 Oligoribonucleotides for the treatment of irritative or inflammatory skin symptoms through RNA interference TLR3, POLR1C, TLR5 LCK 238/4885FYN 1262/4885ING2 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.