Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.39 |
| ▸ | CPB1 | P15086 | 4/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032506 | 0.85 | CYP2E1 (0.40) | CPB2CPB1THRBKMT2A | |
| SCHEMBL9032483 | 0.82 | KDM5A (0.39) | KDM5AKDM5BCPB2CPB1GRIN2D | |
| SCHEMBL4590745 | 0.78 | THRB (0.35) | LMNATHRBKMT2A | |
| SCHEMBL304175 | 0.75 | LMNA (0.46) | LMNAKMT2AMEN1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL27398725 | 0.73 | LMNA (0.45) | LMNAKMT2AMEN1TSHRL3MBTL1 | |
| SCHEMBL31487985 | 0.70 | CYP2E1 (0.40) | CPB2CPB1 | |
| SCHEMBL710279 | 0.69 | KDM5A (0.54) | KDM5AKDM5BCPB2CPB1LMNA | |
| SCHEMBL5656588 | 0.68 | CPB2 (0.48) | KDM5AKDM5BCPB2CPB1GRIN2D | |
| SCHEMBL24925524 | 0.67 | — | — | |
| SCHEMBL2702033 | 0.67 | TDP1 (0.45) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4904564-A | PHENOLIC-FORMALDEHYDE NOVOLAK; DIAZO SENSITIZER; IMIDAZOLE, BENZIMIDAZOLE, TRIAZOLE OR INDAZOLE TO INCREASE SOLUBILITY | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0346650-A2 | Process for imaging multi-layer resist structure | International Business Machines Corporation (US) | 1989-12-20 | — | — | EP | disclosed |
| EP-0139090-B1 | PROCESS FOR THE PRE-TREATMENT OF POLYIMIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-07-27 | — | — | EP | disclosed |
| US-4517254-A | ALKALI METAL HYDROXIDE, AMINOALKYLPOLYACID COMPOUNT | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-14 | — | — | US | disclosed |
| EP-0139090-A1 | Process for the pre-treatment of polyimides | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-05-02 | — | — | EP | disclosed |
| US-4248632-A | ACTIVATION OF A POLYMER SURFACE WITH A PALLADIUM COMPLEX SALT | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |