Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426115 | 0.83 | KMT2A (0.43) | ESR1KMT2A | |
| Bromide SCHEMBL10426793 | 0.82 | KMT2A (0.43) | ESR1KMT2A | |
| SCHEMBL10426114 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2A | |
| SCHEMBL10426725 | 0.81 | BCHE (0.53) | MAOBBCHE | |
| Bromide SCHEMBL10425849 | 0.80 | BCHE (0.53) | MAOBBCHE | |
| SCHEMBL10425941 | 0.80 | ABCB1 (0.43) | MEN1KMT2A | |
| SCHEMBL9779620 | 0.68 | HDAC3 (0.57) | MAOBMAPTRAB9ACYP1A2CYP1B1 | |
| SCHEMBL9779623 | 0.68 | HDAC3 (0.57) | MAOBMAPTRAB9ACYP1A2CYP1B1 | |
| SCHEMBL11403943 | 0.67 | ALDH1A1 (0.46) | MAPTNPSR1MEN1KMT2A | |
| SCHEMBL3500698 | 0.65 | SGMS2 (0.52) | MAPTRAB9ANPSR1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4906634-A | Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents | SCHERING A.G. (DE) | 1990-03-06 | — | — | US | claimed |