SCHEMBL3500698

SCHEMBL3500698

CCN(CC)C(C)Oc1ccccc1C(=O)Nc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SGMS2 Q8NHU3 1/20 0.52
▸ KMT2A Q03164 5/20 0.52
▸ MEN1 O00255 3/20 0.52
▸ POLB P06746 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ KCNK3 O14649 5/20 0.50
▸ KCNK9 Q9NPC2 5/20 0.50
▸ RAB9A P51151 3/20 0.50
▸ ALDH1A1 P00352 2/20 0.49
▸ MCL1 Q07820 1/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ CYP1A2 P05177 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ MAPT P10636 3/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ TP53 P04637 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29493484 0.80 SGMS2 (0.56) SGMS2KMT2AMEN1KCNK3KCNK9
SCHEMBL24239276 0.77 KMT2A (0.60) SGMS2KMT2AMEN1POLBNPSR1
SCHEMBL3805684 0.76 KDM4E (0.57) KMT2AMEN1ALDH1A1CYP1A2CYP2C9
SCHEMBL5504642 0.76 MEN1 (0.83) SGMS2KMT2AMEN1NPSR1KCNK3
SCHEMBL8899486 0.75 ADRA2A (0.43) KMT2AMEN1POLBNPSR1ALDH1A1
SCHEMBL9706157 0.74 ADRA2A (0.40) KMT2AALDH1A1SMN1; SMN2CYP1A2CYP3A4
Acetic Acid SCHEMBL29011401 0.74 KDM4E (0.58) KMT2AMEN1ALDH1A1CYP1A2CYP2C9
Salverine SCHEMBL25064 0.74 ALDH1A1 (0.70) SGMS2KMT2AMEN1POLBNPSR1
Salverine SCHEMBL29360867 0.74 ALDH1A1 (0.70) SGMS2KMT2AMEN1POLBNPSR1
SCHEMBL5852391 0.74 SGMS2 (0.62) SGMS2KMT2AMEN1KCNK3KCNK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 — — US disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 — — US disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 — — US disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 — — EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 — — US disclosed
WO-2007062198-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECHNOLOGY, INC. (US) 2007-05-31 — — WO disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 — — WO disclosed
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