Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10428381 | 0.89 | ALOX5 (0.43) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL10428276 | 0.82 | ALDH1A1 (0.45) | HPGDALDH1A1RAB9ANPC1TSHR | |
| Dimethylamine SCHEMBL10428304 | 0.79 | ALOX5 (0.48) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| SCHEMBL10428348 | 0.78 | ALOX5 (0.73) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| Diethylamine SCHEMBL10428382 | 0.77 | ALOX5 (0.44) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| SCHEMBL10428357 | 0.76 | HPGD (0.49) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL10428430 | 0.76 | PTGS1 (0.49) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| SCHEMBL10428271 | 0.75 | ALOX5 (0.61) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL10428295 | 0.73 | PTGS1 (0.46) | ALOX5PTGS1PTGS2HPGDALDH1A1 | |
| SCHEMBL10428373 | 0.73 | PTGS2 (0.43) | PTGS1PTGS2HPGDALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927835-A | ANTIPYRETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0331195-A2 | Acylphenol derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-09-06 | — | — | EP | disclosed |