Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10428276 | 0.87 | ALDH1A1 (0.45) | SLC6A9POLBELANEGABRA1GABRB1 | |
| SCHEMBL10428373 | 0.84 | PTGS2 (0.43) | POLBELANEGABRA1GABRB1KMO | |
| SCHEMBL10428281 | 0.77 | ALDH1A1 (0.43) | ELANEGABRA1GABRB1ACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL10428319 | 0.73 | GABRA1 (0.46) | GABRA1GABRB1ACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL10428302 | 0.72 | ALOX5 (0.45) | ALDH1A1HTTSMN1; SMN2BCHEMEN1 | |
| Dimethylamine SCHEMBL10428277 | 0.71 | GABRA1 (0.40) | POLBELANEGABRA1GABRB1KMO | |
| Diethylamine SCHEMBL10428374 | 0.71 | ALDH1A1 (0.37) | POLBELANEGABRA1GABRB1KMO | |
| Benzophenone SCHEMBL2321915 | 0.70 | KMT2A (0.58) | ELANEACHEALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11200655 | 0.69 | SLC6A2 (0.48) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL3809998 | 0.69 | KDM4E (0.42) | KMOPTGDR2ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927835-A | ANTIPYRETICS | NIPPON SHINYAKU CO., LTD. (JP) | 1990-05-22 | — | — | US | disclosed |
| EP-0331195-A2 | Acylphenol derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-09-06 | — | — | EP | disclosed |