Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429321 | 0.85 | ADORA3 (0.39) | NOTUMSMN1; SMN2MEN1ALDH1A1HPGD | |
| SCHEMBL10429313 | 0.84 | NOTUM (0.38) | NOTUMNISCHSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10429361 | 0.82 | MAOB (0.36) | IDO1SMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL2121780 | 0.81 | NPSR1 (0.40) | IDO1SMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL7166444 | 0.79 | NOTUM (0.42) | NOTUMIDO1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL10429323 | 0.79 | MAOB (0.40) | NOTUMIDO1 | |
| SCHEMBL10429340 | 0.77 | NOTUM (0.39) | NOTUMSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL10429364 | 0.76 | NOTUM (0.33) | NOTUMMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL10429322 | 0.73 | ALDH1A1 (0.37) | NOTUMSMN1; SMN2MEN1ALDH1A1LMNA | |
| SCHEMBL10429350 | 0.73 | KDR (0.36) | ALDH1A1HPGDKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4920119-A | XANTHINE OXIDASE INHIBITORS; CONTROL OR PREVENTION OF GOUT OR ISCHEMIA | HOFFMANN-LA ROCHE INC. (US) | 1990-04-24 | — | — | US | disclosed |