Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121780 | 0.77 | NPSR1 (0.40) | HPGDL3MBTL1 | |
| SCHEMBL10429347 | 0.74 | ROCK2 (0.50) | — | |
| SCHEMBL10429313 | 0.72 | NOTUM (0.38) | HPGDL3MBTL1 | |
| SCHEMBL10429354 | 0.71 | CTSS (0.44) | — | |
| SCHEMBL10429371 | 0.71 | KDM4E (0.39) | HPGD | |
| SCHEMBL10429350 | 0.70 | KDR (0.36) | HPGD | |
| SCHEMBL10429367 | 0.69 | HPGD (0.47) | HPGDL3MBTL1 | |
| SCHEMBL6936315 | 0.69 | TSHR (0.41) | HPGDL3MBTL1 | |
| SCHEMBL10429340 | 0.68 | NOTUM (0.39) | HPGD | |
| SCHEMBL5381471 | 0.67 | NTRK1 (0.41) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274654-A2 | 1,2,3-Triazin-4(3H)-one derivatives, process for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1988-07-20 | — | — | EP | claimed |
| US-4920119-A | XANTHINE OXIDASE INHIBITORS; CONTROL OR PREVENTION OF GOUT OR ISCHEMIA | HOFFMANN-LA ROCHE INC. (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0274654-A2 | 1,2,3-Triazin-4(3H)-one derivatives, process for their preparation and medicaments containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1988-07-20 | — | — | EP | disclosed |