Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 8/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429856 | 0.82 | ADRA2A (0.43) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Hydrochloric Acid SCHEMBL15412521 | 0.80 | ADRA2A (0.42) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL9706129 | 0.73 | ALDH1A3 (0.39) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Benzofuran SCHEMBL5035535 | 0.72 | CYP2D6 (0.54) | KCNA3PGRADRA2AADRA2BHTR2A | |
| Benzofuran SCHEMBL28188884 | 0.72 | CA4 (0.54) | KCNA3 | |
| SCHEMBL11682289 | 0.71 | BCHE (0.49) | ADRA2AADRA2BHTR2AHRH1KCNH2 | |
| Benzofuran SCHEMBL5860505 | 0.71 | MAOA (0.39) | CA2HTR1BCTNNB1WNT3ACA12 | |
| Benzofuran SCHEMBL22129287 | 0.71 | MAOB (0.44) | CA2CTNNB1WNT3ACA12 | |
| SCHEMBL31681671 | 0.71 | MAOB (0.44) | CA2CTNNB1WNT3ACA12 | |
| Benzofuran SCHEMBL27981826 | 0.71 | MAOA (0.44) | CA2CTNNB1WNT3ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664267-B2 | Parenteral solution containing amiodarone in NNDMA (N,N,-Dimethylacetamide) | ACADEMIC PHARMACEUTICALS INCORPORATED (US) | 2014-03-04 | — | — | US | disclosed |
| US-20080255229-A1 | Parenteral solution containing amiodarone in NNDMA (N,N,-Dimethylacetamide) | ACADEMIC PHARMACEUTICALS INCORPORATED | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255229-A1 | Parenteral solution containing amiodarone in NNDMA (N,N,-Dimethylacetamide) | TNNC1, NPPA, TNNI3 | KCNA3 170/4885PGR 3477/4885ADRA2A 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.