Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526385 | 0.84 | LMNA (0.40) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL27803980 | 0.82 | KMT2A (0.50) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL9527633 | 0.81 | RAB9A (0.50) | LMNAKMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL9525716 | 0.81 | ITGA4 (0.54) | TDP1LMNAKMT2ANPC1RAB9A | |
| SCHEMBL28598894 | 0.78 | ALDH1A1 (0.53) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL23994825 | 0.75 | TDP1 (0.55) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL3667152 | 0.75 | SLC6A2 (0.49) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL10429974 | 0.74 | TDP1 (0.48) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL30522295 | 0.74 | NPC1 (0.69) | TDP1LMNANPC1RAB9AMAPT | |
| SCHEMBL16193532 | 0.74 | NPC1 (0.69) | TDP1LMNANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366542-A1 | 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres | L'OREAL (FR) | 1990-05-02 | — | — | EP | disclosed |