Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.74 |
| ▸ | HPGD | P15428 | 6/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | AR | P10275 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | AHR | P35869 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26605016 | 0.90 | POLH (0.73) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL9137850 | 0.89 | HPGD (0.75) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL4650059 | 0.89 | ATM (0.69) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL10432585 | 0.89 | ALDH1A1 (0.63) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL26604983 | 0.89 | AR (0.67) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL15630238 | 0.86 | HPGD (0.61) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL15619737 | 0.86 | BCHE (0.66) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL9141356 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL253522 | 0.85 | HPGD (0.78) | ALDH1A1HPGDCYP3A4KDM4EMAPT | |
| SCHEMBL1629391 | 0.85 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP3A4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | claimed |
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| EP-2730431-B1 | Rubber composition and tire with rubber containing flavone | GOODYEAR TIRE & RUBBER (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | NANYANG POLYTECHNIC (SG) | 2015-10-15 | — | — | US | disclosed |
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | NANYANG POLYTECHNIC (SG) | 2015-10-15 | — | — | US | disclosed |
| US-20140186277-A1 | Methods and Compositions for Reducing Skin Damage | SHISEIDO CO., LTD. (JP) | 2014-07-03 | — | — | US | disclosed |
| US-20140135433-A1 | TIRE WITH RUBBER CONTAINING FLAVONE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| EP-2730431-A1 | Rubber composition and tire with rubber containing flavone | The Goodyear Tire & Rubber Company (US) | 2014-05-14 | — | — | EP | disclosed |
| US-20110091387-A1 | METHODS AND COMPOSITIONS FOR REDUCING SKIN DAMAGE | THE GENERAL HOSPITAL CORPORATION (US) | 2011-04-21 | — | — | US | disclosed |
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| WO-2006030322-A2 | USE OF FLA VONE/FLA VANONE DERIVATIVES FN THE TREATMENT OR PREVENTION OF RESPIRATORY CONDITIONS | UNIVERSITY OF MANITOBA (CA) | 2006-03-23 | — | — | WO | disclosed |
| US-6872771-B1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1391327-A1 | Tire with rubber containing flavone | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2003057210-A1 | COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| US-20030125264-A1 | Methods For Treating Wounds | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-07-03 | — | — | US | disclosed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305068-A1 | COMPOUNDS AND METHODS FOR MODULATING PROTEIN TRAFFICKING | GOLT1B, NPC1L1, NPC1 | ALDH1A1 3582/4885HPGD 4457/4885CYP3A4 4800/4885 |
| US-20030125264-A1 | Methods For Treating Wounds | FGF2, MMP1, FIBP | ALDH1A1 2440/4885HPGD 558/4885CYP3A4 3010/4885 |
| US-20150291547-A1 | SMALL MOLECULES FOR EXTENDING THE WELL BEING OF CELLS AND METHODS OF USE THEREOF | TERT, POT1, TERF2 | ALDH1A1 2026/4885HPGD 1283/4885CYP3A4 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.