Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CLPP | Q16740 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2923101 | 1.00 | LMNA (0.39) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL1496810 | 1.00 | LMNA (0.39) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL1496673 | 0.87 | ALDH1A1 (0.40) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10433795 | 0.86 | TDP1 (0.38) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10434223 | 0.86 | TDP1 (0.38) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10433794 | 0.86 | TDP1 (0.38) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10918401 | 0.85 | L3MBTL1 (0.39) | LMNAALDH1A1MAPTL3MBTL1GAA | |
| SCHEMBL1496747 | 0.84 | L3MBTL1 (0.40) | LMNAALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL10434023 | 0.84 | ATM (0.35) | LMNAALDH1A1MAPTSRD5A2ATM | |
| SCHEMBL10434021 | 0.84 | ATM (0.35) | LMNAALDH1A1MAPTSRD5A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189847-B2 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5312999-A | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5136059-A | PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |
| EP-0322815-A2 | Propoxybenzene derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |