Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CLPP | Q16740 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496810 | 1.00 | LMNA (0.39) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL8979401 | 1.00 | LMNA (0.39) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL1496673 | 0.87 | ALDH1A1 (0.40) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10433795 | 0.86 | TDP1 (0.38) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10434223 | 0.86 | TDP1 (0.38) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10433794 | 0.86 | TDP1 (0.38) | LMNAALDH1A1MAPTSRD5A2L3MBTL1 | |
| SCHEMBL10918401 | 0.85 | L3MBTL1 (0.39) | LMNAALDH1A1MAPTL3MBTL1GAA | |
| SCHEMBL1496747 | 0.84 | L3MBTL1 (0.40) | LMNAALDH1A1L3MBTL1ATMTDP1 | |
| SCHEMBL10434023 | 0.84 | ATM (0.35) | LMNAALDH1A1MAPTSRD5A2ATM | |
| SCHEMBL10434021 | 0.84 | ATM (0.35) | LMNAALDH1A1MAPTSRD5A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179595-B1 | (R)-2-OCTANOL DEHYDROGENASES, METHODS FOR PRODUCING THE ENZYMES, DNA ENCODING THE ENZYMES, AND METHODS FOR PRODUCING ALCOHOLS USING THE ENZYMES | DAICEL CHEM (JP) | 2010-09-01 | — | — | EP | claimed |
| US-20040126857-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | DAICEL CHEMICAL INDUSTRIES, LTD., A JAPAN CORPORATION | 2004-07-01 | — | — | US | claimed |
| US-20020192783-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2002-12-19 | — | — | US | claimed |
| US-6448449-B2 | RING OPENING OF (R)-PROPYLENE OXIDE WITH ARYLTRIMETHYLSILYL ETHER IN THE PRESENCE OF AN OPTICALLY ACTIVE CATALYST; REACTING WITH AN ALCOHOL IN THE PRESENCE OF AN ACID; REACTING THE REGIOISOMERIC MIXTURE WITH A TRIARYLMETHYL HALILE; | RHODIA CHIREX, INC. | 2002-09-10 | — | — | US | claimed |
| EP-1179595-A1 | (R)-2-OCTANOL DEHYDROGENASE, PROCESS FOR PRODUCING THE ENZYME, DNA ENCODING THE ENZYME AND PROCESS FOR PRODUCING ALCOHOL BY USING THE SAME | Daicel Chemical Industries, Ltd. (JP) | 2002-02-13 | — | — | EP | claimed |
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | RHODIA CHIREX, INC. | 2002-01-17 | — | — | US | claimed |
| EP-1179595-B1 | (R)-2-OCTANOL DEHYDROGENASES, METHODS FOR PRODUCING THE ENZYMES, DNA ENCODING THE ENZYMES, AND METHODS FOR PRODUCING ALCOHOLS USING THE ENZYMES | DAICEL CHEM (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-1367132-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE PROPOXYANILINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2009-08-12 | — | — | EP | disclosed |
| US-7217560-B2 | Process for preparation of optically active propoxyaniline derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-7217560-B2 | Process for preparation of optically active propoxyaniline derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |
| US-7202069-B2 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-10 | — | — | US | disclosed |
| US-7189847-B2 | Process for producing benzoxazine derivative and production intermediate thereof | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-13 | — | — | US | disclosed |
| JP-2004313033-A | NEW CARBONYL REDUCTASE, GENE ENCODING THE SAME AND USE THEREOF | DAIICHI FINE CHEMICAL CO LTD | 2004-11-11 | — | — | JP | disclosed |
| US-6172268-B1 | REACTING A HYDROXY AROMATIC COMPOUND WITH A PROPYLENE OXIDE IN PRESENCE OF METAL COMPLEX CATALYST | ASAHI GLASS COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| JP-2000063314-A | PRODUCTION OF OPTICALLY ACTIVE 1-SUBSTITUTED-2-PROPANOL | ASAHI GLASS CO LTD | 2000-02-29 | — | — | JP | disclosed |
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5312999-A | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5136059-A | PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |
| EP-0322815-A2 | Propoxybenzene derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007090-A1 | Process for preparation of (R)-1- (aryloxy)propan-2-ol | TOP1, POLN, RIF1 | LMNA 389/4885ALDH1A1 180/4885MAPT 3549/4885 |
| US-20040126857-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | OGA, HOGA1, ADH1A | LMNA 3974/4885ALDH1A1 41/4885MAPT 3790/4885 |
| US-20020192783-A1 | (R)-2-octanol dehydrogenases, methods for producing the enzymes, DNA encoding the enzymes, and methods for producing alcohols using the enzymes | OGA, HOGA1, ADH1A | LMNA 3974/4885ALDH1A1 41/4885MAPT 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.