Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12888669 | 0.78 | L3MBTL1 (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL10434832 | 0.76 | LMNA (0.43) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL9763408 | 0.74 | CYP1A2 (0.43) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL1067804 | 0.72 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL12873600 | 0.71 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL14782540 | 0.71 | LMNA (0.52) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL439716 | 0.69 | LMNA (0.59) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL423183 | 0.69 | PDE2A (0.61) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL10827038 | 0.69 | KDM4E (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 | |
| SCHEMBL8656719 | 0.67 | LMNA (0.48) | LMNASMN1; SMN2L3MBTL1CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356828-A2 | Process for the preparation of sulfonyl isothiourea | BAYER AG (DE) | 1990-03-07 | — | — | EP | disclosed |