Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 6/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436792 | 0.81 | HTR2C (0.53) | HTR2CHTR2BMAPTMEN1KMT2A | |
| SCHEMBL10436769 | 0.81 | HTR2C (0.56) | HTR2CHTR2BMAPTALDH1A1MEN1 | |
| SCHEMBL10436783 | 0.80 | HTR2C (0.54) | HTR2CHTR2BMEN1KMT2AKDR | |
| SCHEMBL10436636 | 0.78 | HTR2C (0.49) | HTR2CHTR2BMAPTALDH1A1MEN1 | |
| SCHEMBL10436793 | 0.77 | PDGFRA (0.63) | HTR2CHTR2BMAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7664592 | 0.76 | HTR2C (0.98) | HTR2CHTR2BMAPTALDH1A1MEN1 | |
| SCHEMBL7370903 | 0.74 | HTR2C (0.70) | HTR2CHTR2BMAPTMEN1KMT2A | |
| SCHEMBL7375771 | 0.73 | HTR2C (0.81) | HTR2CHTR2BMAPTALDH1A1MEN1 | |
| SCHEMBL7447310 | 0.73 | HTR2C (0.67) | HTR2CHTR2BMAPTALDH1A1MEN1 | |
| SCHEMBL7659932 | 0.73 | HTR2C (0.67) | HTR2CHTR2BMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |