Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.36 |
| ▸ | TUBB | P07437 | 2/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509766 | 0.84 | TUBB4A (0.43) | APPMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL9507449 | 0.74 | TUBB4A (0.43) | APPMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL9506016 | 0.72 | TUBB4A (0.38) | MAPTALDH1A1LMNAMAPK1GFER | |
| SCHEMBL10437543 | 0.70 | PDGFRB (0.38) | APPMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL183546 | 0.68 | APP (0.40) | APPMAPTALDH1A1MAPK1HSD17B10 | |
| SCHEMBL7690993 | 0.67 | ALDH1A1 (0.42) | APPMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL9538022 | 0.67 | MAOB (0.44) | MAPTALDH1A1GFERHSD17B10KDM4E | |
| SCHEMBL9157682 | 0.67 | TDP1 (0.41) | MAPTTSHRTP53ESR2 | |
| SCHEMBL7702845 | 0.65 | PDGFRB (0.38) | APPMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL28334181 | 0.65 | CA12 (0.39) | APPALDH1A1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396828-A1 | Unsymmetrical squaraine compositions and photoconductive imaging members using such compositions | XEROX CORPORATION (US) | 1990-11-14 | — | — | EP | disclosed |