Phosphoric Acid

Phosphoric Acid

SCHEMBL9017459

O=P(O)(O)O.Oc1cccc(Oc2ccccc2)c1-c1ccccc1

nearest known ligand 0.55

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAPDH P04406 1/20 0.42
TTR P02766 2/20 0.41
GAA P10253 2/20 0.40
CTNNB1 P35222 1/20 0.40
SRC P12931 1/20 0.39
LMNA P02545 1/20 0.39
KMT2A Q03164 1/20 0.39
GGPS1 O95749 1/20 0.38
PNLIP P16233 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 1/20 0.38
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL28910336 0.92 GAPDH (0.40) GAPDHTTRGAACTNNB1SRC
SCHEMBL27958338 0.92 GAPDH (0.44) GAPDHTTRGAACTNNB1LMNA
SCHEMBL7639737 0.84 GAPDH (0.39) GAPDHTTRGAACTNNB1LMNA
SCHEMBL4625341 0.82 HSD17B10 (0.43) GAPDHGAALMNAKMT2AKDM4E
Pyrophosphoric Acid SCHEMBL10438540 0.82 SRC (0.44) GAACTNNB1SRCLMNAKMT2A
Phosphoric Acid SCHEMBL28725997 0.81 CAMK2A (0.42) TTRSRC
SCHEMBL6257211 0.81 LMNA (0.45) LMNAKMT2APNLIPHTT
Phosphoric Acid SCHEMBL14939153 0.80 HDAC4 (0.47) LMNAHSD17B10HTT
Phosphoric Acid SCHEMBL27657596 0.80 HDAC4 (0.47) LMNAHSD17B10HTT
Phosphoric Acid SCHEMBL10790076 0.76 CTNNB1 (0.39) TTRCTNNB1SRCKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117976982-A Sodium ion battery electrolyte, preparation method thereof and sodium ion battery 桂林电子科技大学 2024-05-03 CN claimed
US-5560849-A CONTAINING ARYL DIPHOSPHATE ESTER; HIGH TEMPERATURE LUBRICANT FMC CORPORATION (US) 1996-10-01 US disclosed