SCHEMBL10439499 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	SSTR3	P32745	1/20	0.71

▸	PDF	Q9HBH1	1/20	0.57

▸	CALCRL	Q16602	1/20	0.49

▸	MMP1	P03956	1/20	0.45

▸	FCER2	P06734	1/20	0.45

▸	OPRK1	P41145	4/20	0.44

▸	OPRM1	P35372	2/20	0.44

▸	GHSR	Q92847	1/20	0.44

▸	SMN1; SMN2	Q16637	2/20	0.43

▸	NPC1	O15118	1/20	0.43

▸	TP53	P04637	1/20	0.43

▸	RAB9A	P51151	1/20	0.43

▸	MC4R	P32245	1/20	0.43

▸	PSMB5	P28074	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8365389	1.00	SSTR3 (0.71)	SSTR3PDFCALCRLMMP1FCER2
SCHEMBL8405097	0.92	SSTR3 (0.70)	SSTR3PDFCALCRLMMP1FCER2
SCHEMBL8000347	0.91	PDF (0.67)	SSTR3PDFSMN1; SMN2
SCHEMBL29512267	0.89	SSTR3 (0.57)	SSTR3PDFMMP1FCER2OPRK1
SCHEMBL27750016	0.87	PDF (0.61)	SSTR3PDFMMP1OPRK1OPRM1
SCHEMBL386663	0.87	PDF (0.61)	SSTR3PDFMMP1OPRK1OPRM1
SCHEMBL547491	0.87	PDF (0.61)	SSTR3PDFMMP1OPRK1OPRM1
Hydrochloric Acid SCHEMBL3481900	0.86	PDF (0.60)	SSTR3PDFMMP1OPRK1OPRM1
Hydrochloric Acid SCHEMBL3482618	0.86	PDF (0.60)	SSTR3PDFMMP1OPRK1OPRM1
Hydrochloric Acid SCHEMBL8853773	0.86	PDF (0.60)	SSTR3PDFMMP1OPRK1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0385952-A2	Use of a naphthalenmethanamino derivative as antiinflammatory agent and pharmaceutical compositions containing it	SANDOZ AG (CH)	1990-09-05	—	—	EP	disclosed