Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.70 |
| ▸ | Q9HBH1 | 1/20 | 0.57 | |
| ▸ | PSMB5 | P28074 | 2/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | FCER2 | P06734 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439499 | 0.92 | SSTR3 (0.71) | SSTR3PDFPSMB5CALCRLMMP1 | |
| SCHEMBL8365389 | 0.92 | SSTR3 (0.71) | SSTR3PDFPSMB5CALCRLMMP1 | |
| SCHEMBL30541925 | 0.88 | SSTR3 (0.56) | SSTR3PDFPSMB5PSMB1F2RL1 | |
| SCHEMBL29937990 | 0.83 | SSTR3 (1.00) | SSTR3PDFCALCRL | |
| SCHEMBL8000347 | 0.82 | PDF (0.67) | SSTR3PDFPLG | |
| SCHEMBL30037909 | 0.82 | PDF (0.61) | SSTR3PDFPSMB5PSMB1F2RL1 | |
| SCHEMBL30816049 | 0.82 | PSMB5 (0.54) | SSTR3PSMB5PSMB1F2RL1MMP1 | |
| SCHEMBL29429777 | 0.82 | GHSR (0.56) | F2PLGOPRM1OPRK1GHSR | |
| SCHEMBL29740041 | 0.81 | SSTR3 (0.59) | SSTR3PSMB5PSMB1MMP1FCER2 | |
| SCHEMBL29512267 | 0.81 | SSTR3 (0.57) | SSTR3PDFF2RL1MMP1FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968782-A | NUCLEIC ACID SEQUENCE CODING POLYPEPTIDE ENZYME WITH ENTEROKINASE SENSITIVITY WHICH CAN BE USED FOR TREATING DISORDERS MEDIATED BY THROMBUS CLOT FORMATION | BRIGHAM AND WOMENS'S HOSPITAL, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1998024886-A1 | MAST CELL PROTEASE THAT CLEAVES FIBRINOGEN | BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 1998-06-11 | — | — | WO | disclosed |