Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.57 |
| ▸ | Q9HBH1 | 1/20 | 0.46 | |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8365389 | 0.89 | SSTR3 (0.71) | SSTR3PDFMMP1FCER2MC4R | |
| SCHEMBL10439499 | 0.89 | SSTR3 (0.71) | SSTR3PDFMMP1FCER2MC4R | |
| SCHEMBL8405097 | 0.81 | SSTR3 (0.70) | SSTR3PDFMMP1FCER2OPRK1 | |
| SCHEMBL8000347 | 0.80 | PDF (0.67) | SSTR3PDFSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2108111 | 0.79 | GNPAT (0.60) | OPRK1OPRM1GHSR | |
| SCHEMBL1711761 | 0.79 | GNPAT (0.60) | OPRK1OPRM1GHSR | |
| SCHEMBL2108121 | 0.79 | GNPAT (0.60) | OPRK1OPRM1GHSR | |
| SCHEMBL1711756 | 0.79 | GNPAT (0.60) | OPRK1OPRM1GHSR | |
| SCHEMBL31181294 | 0.77 | GNPAT (0.55) | OPRK1OPRM1GHSR | |
| SCHEMBL8170666 | 0.75 | GNPAT (0.58) | OPRK1OPRM1GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12534722-B2 | Euglobulin-based method for determining the biological activity of defibrotide | GENTIUM S.R.L. (IT) | 2026-01-27 | — | — | US | disclosed |
| US-12529052-B2 | Euglobulin-based method for determining the biological activity of defibrotide | GENTIUM S.R.L. (IT) | 2026-01-20 | — | — | US | disclosed |
| US-20250236867-A1 | EUGLOBULIN-BASED METHOD FOR DETERMINING THE BIOLOGICAL ACTIVITY OF DEFIBROTIDE | GENTIUM S.R.L. (IT) | 2025-07-24 | — | — | US | disclosed |
| US-20250236866-A1 | EUGLOBULIN-BASED METHOD FOR DETERMINING THE BIOLOGICAL ACTIVITY OF DEFIBROTIDE | GENTIUM S.R.L. (IT) | 2025-07-24 | — | — | US | disclosed |
| US-20250075206-A1 | EUGLOBULIN-BASED METHOD FOR DETERMINING THE BIOLOGICAL ACTIVITY OF DEFIBROTIDE | GENTIUM S R L (IT) | 2025-03-06 | — | — | US | disclosed |
| US-11746348-B2 | Euglobulin-based method for determining the biological activity of defibrotide | GENTIUM S.R.L. (IT) | 2023-09-05 | — | — | US | disclosed |
| CN-110079580-B | Euglobulin-based method for determining the biological activity of defibrotide | 真蒂奥姆责任有限公司 | 2022-12-06 | — | — | CN | disclosed |
| US-11236328-B2 | Euglobulin-based method for determining the biological activity of defibrotide | GENTIUM S.R.L. (IT) | 2022-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529052-B2 | Euglobulin-based method for determining the biological activity of defibrotide | FGB, PLG, F2 | SSTR3 2629/4885PDF 181/4885MMP1 1015/4885 |
| US-12534722-B2 | Euglobulin-based method for determining the biological activity of defibrotide | FGB, PLG, F2 | SSTR3 2768/4885PDF 164/4885MMP1 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.