Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.71 |
| ▸ | Q9HBH1 | 1/20 | 0.57 | |
| ▸ | CALCRL | Q16602 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439499 | 1.00 | SSTR3 (0.71) | SSTR3PDFCALCRLMMP1FCER2 | |
| SCHEMBL8405097 | 0.92 | SSTR3 (0.70) | SSTR3PDFCALCRLMMP1FCER2 | |
| SCHEMBL8000347 | 0.91 | PDF (0.67) | SSTR3PDFSMN1; SMN2 | |
| SCHEMBL29512267 | 0.89 | SSTR3 (0.57) | SSTR3PDFMMP1FCER2OPRK1 | |
| SCHEMBL27750016 | 0.87 | PDF (0.61) | SSTR3PDFMMP1OPRK1OPRM1 | |
| SCHEMBL386663 | 0.87 | PDF (0.61) | SSTR3PDFMMP1OPRK1OPRM1 | |
| SCHEMBL547491 | 0.87 | PDF (0.61) | SSTR3PDFMMP1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL3481900 | 0.86 | PDF (0.60) | SSTR3PDFMMP1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL3482618 | 0.86 | PDF (0.60) | SSTR3PDFMMP1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL8853773 | 0.86 | PDF (0.60) | SSTR3PDFMMP1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808458-A4 | DIOXETANE COMPOUNDS FOR THE CHEMILUMINESCENT DETECTION OF PROTEASES, METHODS OF USE AND KITS THEREFORE | TROPIX INC (US) | 1999-06-09 | — | — | EP | disclosed |
| US-5871938-A | DETECTION OF PROTEASE, INCUBATION, BONDING TO DNA AND ANTIBODIES | TROPIX, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| US-5843681-A | Dioxetane compounds for the chemiluminescent detection of proteases, methods of use and kits therefore | TROPIX, INC. (US) | 1998-12-01 | — | — | US | disclosed |
| EP-0808458-A1 | DIOXETANE COMPOUNDS FOR THE CHEMILUMINESCENT DETECTION OF PROTEASES, METHODS OF USE AND KITS THEREFORE | TROPIX, INC. (US) | 1997-11-26 | — | — | EP | disclosed |
| US-5591591-A | Dioxetane compounds for the chemiluminescent detection of proteases, methods of use and kits therefore | TROPIX, INC. (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996024849-A1 | DIOXETANE COMPOUNDS FOR THE CHEMILUMINESCENT DETECTION OF PROTEASES, METHODS OF USE AND KITS THEREFORE | TROPIX, INC. (US) | 1996-08-15 | — | — | WO | disclosed |