Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664015 | 0.81 | ALDH1A1 (0.43) | GAAL3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL9046783 | 0.78 | OPRM1 (0.40) | EGLN1OPRM1OPRD1P2RX3GAA | |
| SCHEMBL9044324 | 0.77 | MAPT (0.48) | EGLN1P2RX3GAAL3MBTL1ATG4B | |
| SCHEMBL10440330 | 0.76 | OPRM1 (0.44) | EGLN1OPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL12173763 | 0.73 | OPRM1 (0.46) | EGLN1OPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL9045495 | 0.71 | OPRM1 (0.45) | OPRM1OPRD1OPRK1P2RX3GRIN2D | |
| SCHEMBL8019976 | 0.69 | P2RX3 (0.48) | EGLN1OPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL9045204 | 0.69 | MAOB (0.53) | EGLN1P2RX3L3MBTL1DAGLA | |
| SCHEMBL14349927 | 0.69 | P2RX3 (0.48) | P2RX3L3MBTL1HRH3 | |
| SCHEMBL7662633 | 0.69 | MEN1 (0.43) | GAACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366085-A2 | Tetrahydropyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-02 | — | — | EP | disclosed |