Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25015682 | 0.84 | ALDH1A1 (0.49) | OPRM1OPRD1OPRK1KDM4EP2RX3 | |
| SCHEMBL14349927 | 0.83 | P2RX3 (0.48) | KDM4EP2RX3 | |
| SCHEMBL28471534 | 0.82 | IL6 (0.46) | OPRM1OPRD1OPRK1P2RX3GRIN2D | |
| SCHEMBL8026494 | 0.80 | L3MBTL1 (0.44) | KDM4EP2RX3 | |
| SCHEMBL16839922 | 0.80 | P2RX3 (0.49) | OPRM1OPRD1OPRK1P2RX3GRIN2D | |
| SCHEMBL9829679 | 0.79 | L3MBTL1 (0.45) | KDM4EP2RX3 | |
| SCHEMBL13181088 | 0.78 | ALDH1A1 (0.52) | OPRM1OPRD1OPRK1KDM4EP2RX3 | |
| SCHEMBL8019976 | 0.77 | P2RX3 (0.48) | OPRM1OPRD1OPRK1P2RX3 | |
| SCHEMBL9045204 | 0.77 | MAOB (0.53) | KDM4EP2RX3 | |
| SCHEMBL15014092 | 0.77 | SMN1; SMN2 (0.50) | KDM4EP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366085-B1 | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-04-17 | — | — | EP | disclosed |
| CN-1031265-C | Tetrahydropyrimidine-containing pest control compositions | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-03-13 | — | — | CN | disclosed |
| CN-1102828-A | Tetrahydropyrimidines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-05-24 | — | — | CN | disclosed |
| US-5084459-A | Insecticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| CN-1042149-A | Tetrahydropyrimidines, their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-05-16 | — | — | CN | disclosed |
| EP-0366085-A2 | Tetrahydropyrimidines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-05-02 | — | — | EP | disclosed |