Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | GALR3 | O60755 | 2/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PDE6D | O43924 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443754 | 0.87 | ALDH1A1 (0.49) | TP53ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL10443491 | 0.86 | TNF (0.68) | TP53ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL10443034 | 0.84 | TP53 (0.73) | TP53ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL10443449 | 0.83 | RAB9A (0.66) | TP53HTTLMNASMN1; SMN2PPARG | |
| SCHEMBL10443931 | 0.82 | HDAC1 (0.58) | TP53ALDH1A1KDM4EHTTLMNA | |
| SCHEMBL10443392 | 0.81 | PPARG (0.72) | PPARGAGTR1AGTR2 | |
| SCHEMBL8394773 | 0.81 | PPARG (0.71) | PPARGAGTR1AGTR2 | |
| SCHEMBL10443531 | 0.80 | LMNA (0.55) | TP53ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL152719 | 0.80 | TNF (0.65) | TP53ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL10443499 | 0.79 | AGTR1 (0.72) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |