Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.59 |
| ▸ | TUBB | P07437 | 1/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8802574 | 0.88 | MTNR1A (0.67) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL9304037 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL7056738 | 0.81 | HTR1A (0.48) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL5426900 | 0.79 | PTPN5 (0.78) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL8805501 | 0.77 | MTNR1A (0.60) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL7696761 | 0.76 | AKR1C2 (0.61) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL31034424 | 0.76 | HPGD (0.58) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL8805832 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL9401166 | 0.75 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL9401169 | 0.75 | MTNR1A (0.58) | MTNR1AMTNR1BALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375133-A1 | Alpha-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents | THE UPJOHN COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |