Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401142 | 0.87 | KMT2A (0.49) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL9401130 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL10444002 | 0.75 | MTNR1A (0.67) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL9401166 | 0.74 | MTNR1A (0.58) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL9304037 | 0.73 | MTNR1A (1.00) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL8802574 | 0.70 | MTNR1A (0.67) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL9535590 | 0.69 | KDM4E (0.58) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL8805501 | 0.68 | MTNR1A (0.60) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL7696761 | 0.67 | AKR1C2 (0.61) | MTNR1AMTNR1BKMT2AMEN1ALDH1A1 | |
| SCHEMBL9145256 | 0.66 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |