Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401139 | 0.87 | ALDH1A1 (0.54) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL9401124 | 0.84 | ALDH1A1 (0.57) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL8805832 | 0.76 | MTNR1A (0.63) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL9401135 | 0.76 | ALDH1A1 (0.57) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL10444002 | 0.75 | MTNR1A (0.67) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL9401169 | 0.74 | MTNR1A (0.58) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL8805501 | 0.74 | MTNR1A (0.60) | MTNR1AMTNR1BKDM4EALDH1A1MEN1 | |
| SCHEMBL9304037 | 0.73 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL8802574 | 0.70 | MTNR1A (0.67) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL28680395 | 0.69 | MTNR1A (0.56) | MTNR1AMTNR1BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314908-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0549916-A2 | Compounds useful as antiproliferative agents | WHITBY RESEARCH, Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5206377-A | Compounds useful as antiproliferative agents | WHITBY RESEARCH, INC. (US) | 1993-04-27 | — | — | US | disclosed |