Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.31 |
| ▸ | TPO | P07202 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10445044 | 0.80 | SIRT2 (0.36) | MPOALDH1A1KMT2A | |
| SCHEMBL7213284 | 0.74 | ALDH1A1 (0.43) | MPONPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL9357392 | 0.70 | ALDH1A1 (0.34) | MPONPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL9357376 | 0.69 | DUT (0.51) | MPONPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL9353877 | 0.69 | ALDH1A1 (0.42) | MPONPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL26034731 | 0.68 | MTNR1A (0.40) | MPONPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL26039901 | 0.67 | MPO (0.36) | MPONPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL4378111 | 0.67 | RAB9A (0.51) | NPC1RAB9AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL10445013 | 0.67 | MPO (0.36) | MPONPC1RAB9AMTNR1AMTNR1B | |
| SCHEMBL26064071 | 0.65 | MPO (0.35) | MPONPC1RAB9AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371139-A1 | 6-SUBSTITUTED ACYCLICPYRIMIDINE NUCLEOSIDE DERIVATIVES AND ANTIVIRAL AGENTS CONTAINING SAME AS ACTIVE INGREDIENTS | Mitsubishi Chemical Corporation (JP) | 1990-06-06 | — | — | EP | disclosed |