Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989049 | 0.93 | CHRNB2 (0.46) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL1046760 | 0.90 | NOS1 (0.50) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL1047648 | 0.88 | NOS1 (0.51) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL8778626 | 0.86 | NOS1 (0.52) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL1046516 | 0.86 | NOS1 (0.52) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL28644836 | 0.83 | LTA4H (0.50) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL535429 | 0.83 | MAOB (0.52) | LTA4HNOS1MAOBALDH1A1AOC3 | |
| SCHEMBL10458622 | 0.81 | MAOB (0.53) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL5074587 | 0.79 | LTA4H (0.50) | LTA4HNOS1MAOBCHRNB2CHRNB4 | |
| SCHEMBL4332998 | 0.79 | LTA4H (0.50) | LTA4HNOS1MAOBCHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146996-A1 | XANTHINE COMPOUNDS HAVING A POSITIVE ALLOSTERIC GABAB RECEPTOR MODULATOR EFFECT | AstraZeneca AB (SE) | 2010-01-27 | — | — | EP | claimed |
| US-20090023704-A1 | Novel Compounds 737 | ASTRAZENECA AB (SE) | 2009-01-22 | — | — | US | claimed |
| WO-2008130314-A1 | XANTHINE COMPOUNDS HAVING A POSITIVE ALLOSTERIC GABAB RECEPTOR MODULATOR EFFECT | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | claimed |
| EP-2594553-B1 | ALKOXYIMINO DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2019-03-13 | — | — | EP | disclosed |
| US-20150224099-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 2015-08-13 | — | — | US | disclosed |
| US-8987304-B2 | Antituberculous composition comprising oxazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-24 | — | — | US | disclosed |
| US-8895035-B2 | Alkoxyimino derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2594553-A1 | ALKOXYIMINO DERIVATIVE AND PEST CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-20130102568-A1 | ALKOXYIMINO DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. AND IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-5817826-A | INHIBIT FORMATION OF PROSTAGLANDINS, LEUKOTRIENES; ANTIINFLAMMATION AGENTS | SHIONOGI & CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| CN-1192200-A | Phenylacetic acid derivatives, process and intermediates for their preparation, and their use as pest-killing compositions and fungicides | BASF AG (DE) | 1998-09-02 | — | — | CN | disclosed |
| CN-1166829-A | Iminooxymethylene anilides, process and intermediate products for preparing the same and pesticides containing the same | BASF AG (DE) | 1997-12-03 | — | — | CN | disclosed |
| CN-1161687-A | Phenylacetic acid alkyl esters | BASF AG (DE) | 1997-10-08 | — | — | CN | disclosed |
| WO-1997033874-A1 | PYRIMIDYL PHENYL AND BENZYL ETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-18 | — | — | WO | disclosed |
| CN-1143361-A | Phenylacetic acid derivatives, their preparation and intermediates, and compositions containing them | BASF AG (DE) | 1997-02-19 | — | — | CN | disclosed |
| CN-1115576-A | Oxazolinone derivative having intracellular phospholipase A2 inhibitor activity | SHIONOGI & CO (JP) | 1996-01-24 | — | — | CN | disclosed |
| EP-0675114-A1 | OXAZOLINONE DERIVATIVE HAVING INTRACELLULAR PHOSPHOLIPASE A 2? INHIBITOR ACTIVITY | SHIONOGI & CO., LTD. (JP) | 1995-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150224099-A1 | ANTITUBERCULOUS COMPOSITION COMPRISING OXAZOLE COMPOUNDS | OXA1L, ARG1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | LTA4H 813/4885NOS1 295/4885MAOB 1633/4885 |
| US-20130102568-A1 | ALKOXYIMINO DERIVATIVE AND PEST CONTROL AGENT | O60361, ALK, DDT | LTA4H 2368/4885NOS1 1280/4885MAOB 1641/4885 |
| US-20090023704-A1 | Novel Compounds 737 | GRPR, GABRB1, GABBR1 | LTA4H 959/4885NOS1 2115/4885MAOB 623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.