Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451670 | 0.90 | KDM4E (0.49) | ELANEALDH1A1NPSR1MAPTHTT | |
| SCHEMBL1434118 | 0.85 | ALDH1A1 (0.59) | ALDH1A1NPSR1MAPTHTTKDM4E | |
| SCHEMBL9242326 | 0.84 | ELANE (0.54) | ELANEDRD2DRD1DRD3ABCB1 | |
| SCHEMBL11784830 | 0.83 | ALDH1A1 (0.57) | ALDH1A1NPSR1MAPTHTTKDM4E | |
| SCHEMBL10937345 | 0.81 | DRD2 (0.56) | ELANEDRD2DRD1DRD3ABCB1 | |
| SCHEMBL17859344 | 0.80 | LMNA (0.60) | ABCB1ALDH1A1MAPTHTTKDM4E | |
| SCHEMBL3441526 | 0.80 | HTT (0.54) | ALDH1A1RAB9AMAPTHTTKDM4E | |
| SCHEMBL6789664 | 0.80 | KDM4E (0.47) | ALDH1A1NPSR1MAPTHTTKDM4E | |
| SCHEMBL769670 | 0.80 | DRD2 (0.57) | ELANEDRD2DRD1DRD3ABCB1 | |
| SCHEMBL30149165 | 0.80 | DRD2 (0.57) | ELANEDRD2DRD1DRD3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4018452-A | — | — | None | — | — | JP | disclosed |
| JP-H0418452-A | ENAMINE DERIVATIVE, ITS PRECURSOR, PRODUCTION THEREOF AND ELECTROPHOTOGRAPHIC SENSITIVE UNIT CONTAINING THE SAME ENAMINE DERIVATIVE | HITACHI CHEM CO LTD | 1992-01-22 | — | — | JP | disclosed |