Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10451670 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1PRMT5MRGPRX1NPSR1 | |
| SCHEMBL1434118 | 0.84 | ALDH1A1 (0.59) | KDM4EALDH1A1PRMT5MRGPRX1ALOX15 | |
| SCHEMBL11786107 | 0.83 | MEN1 (0.59) | KDM4EALDH1A1PRMT5MRGPRX1NPSR1 | |
| SCHEMBL3441526 | 0.83 | HTT (0.54) | KDM4EALDH1A1CYP1A2CYP2C9KMT2A | |
| SCHEMBL11784830 | 0.83 | ALDH1A1 (0.57) | KDM4EALDH1A1PRMT5MRGPRX1NPSR1 | |
| SCHEMBL17859344 | 0.83 | LMNA (0.60) | KDM4EALDH1A1PRMT5HCRTR1HCRTR2 | |
| SCHEMBL11784824 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1PRMT5MRGPRX1NPSR1 | |
| SCHEMBL27994489 | 0.81 | KDM4E (0.46) | KDM4EALDH1A1PRMT5MRGPRX1NPSR1 | |
| SCHEMBL15865897 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1ALOX15HCRTR1SMN1; SMN2 | |
| SCHEMBL9715644 | 0.80 | ELANE (0.53) | KDM4EALDH1A1NPSR1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220409-A1 | Flecainide synthesis | MCDANIEL WILLIAM C | 2004-11-04 | — | — | US | claimed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220409-A1 | Flecainide synthesis | KCNH1, CYP3A43, CYP2F1 | KDM4E 455/4885ALDH1A1 450/4885PRMT5 4648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.