SCHEMBL10453380

SCHEMBL10453380

COc1ccc(O)c(-n2n3c4ccccc4n23)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 7/20 0.43
▸ MAPT P10636 5/20 0.43
▸ MEN1 O00255 5/20 0.43
▸ ALDH1A1 P00352 4/20 0.43
▸ KDM4E B2RXH2 3/20 0.43
▸ GAA P10253 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ THRB P10828 1/20 0.43
▸ RECQL P46063 1/20 0.43
▸ BLM P54132 1/20 0.43
▸ MCL1 Q07820 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ HPGD P15428 4/20 0.42
▸ HTT P42858 2/20 0.42
▸ HSD17B10 Q99714 2/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ ERN1 O75460 1/20 0.41
▸ LMNA P02545 4/20 0.41
▸ CYP1A2 P05177 3/20 0.41
▸ PGR P06401 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14202614 0.87 LMNA (0.44) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL13702346 0.83 BACE1 (0.33) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL9915554 0.80 MMP1 (0.32) —
SCHEMBL11938474 0.80 FGFR1 (0.42) KMT2AMAPTMEN1ALDH1A1SMN1; SMN2
SCHEMBL9002752 0.80 FGFR1 (0.42) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL9002344 0.76 — —
SCHEMBL10453379 0.75 CA2 (0.57) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL9002493 0.73 ALDH1A1 (0.48) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL17681914 0.73 BACE1 (0.49) KMT2AMAPTMEN1ALDH1A1KDM4E
SCHEMBL29768260 0.72 RAB9A (0.64) KMT2AMAPTMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 — — US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 — — US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 — — US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 — — US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 — — US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 — — US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 — — US disclosed
US-9097837-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-08-04 — — US disclosed
US-9097837-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-08-04 — — US disclosed
US-20110020600-A1 Cellulose Acylate Film, Method for Producing Same, Optically Compensatory Film, Anti-Reflection Film, Polarizing Plate and Image Display Device FUJIFILM CORPORATION (JP) 2011-01-27 — — US disclosed
US-7671947-B2 Optical film, optical compensation film, polarizing plate, liquid crystal display unit and self luminous display unit FUJIFILM CORPORATION (JP) 2010-03-02 — — US disclosed
US-20090224217-A1 CELLULOSE ACYLATE FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2009-09-10 — — US disclosed
US-20090192256-A1 POLYMER BLEND FILM CONTAINING CYCLIC POLYOLEFIN FUJIFILM CORPORATION (JP) 2009-07-30 — — US disclosed
US-20090122237-A1 POLYMER FILM, METHOD FOR PRODUCING POLYMER FILM, OPTICAL FILM AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2009-05-14 — — US disclosed
US-20090086125-A1 Process for producing cellulose acylate film, cellulose acylate film, optically- compensatory film, polarizing plate and liquid-crystal display device FUJIFILM CORPORATIN (JP) 2009-04-02 — — US disclosed
US-20080309860-A1 Optical Film, Optical Compensation Film, Polarizing Plate, Liquid Crystal Display Unit and Self Luminous Display Unit FUJIFILM CORPORATION (JP) 2008-12-18 — — US disclosed
US-20080173215-A1 Cellulose Acylate Film, and Polarizing Plate and Liquid-Crystal Display Device Using the Same FUJIFILM CORPORATION (JP) 2008-07-24 — — US disclosed
US-20070292635-A1 Optical Compensation Polarizing Plate, Image Display Unit and Liquid Crystal Display Unit FUJIFILM CORPORATION (JP) 2007-12-20 — — US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 — — US disclosed
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