Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455034 | 0.87 | PSIP1 (0.74) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10619867 | 0.84 | ALDH1A1 (0.47) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9770084 | 0.81 | ALDH1A1 (0.53) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1251768 | 0.80 | PSIP1 (0.58) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL23351954 | 0.77 | PSIP1 (0.61) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL86088 | 0.77 | ALDH1A1 (0.67) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL2642650 | 0.77 | PSIP1 (0.61) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9908320 | 0.75 | PSIP1 (0.68) | PSIP1GAAALDH1A1CA2KMT2A | |
| SCHEMBL5375 | 0.75 | PLCG1 (0.70) | PSIP1GAAALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL1657371 | 0.75 | CA2 (0.59) | PSIP1GAAMMP8CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | claimed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | claimed |
| US-6908920-B2 | Pyrimidine derivatives | ASTRAZENECA AB (SE) | 2005-06-21 | — | — | US | disclosed |
| US-4960768-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| US-4863954-A | Acyloxythiophene-carboxamide fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4767757-A | Acyloxythiophene-carboxamide fungicides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | disclosed |
| EP-0241735-A2 | Acyloxythiophene carbon amide | BAYER AG (DE) | 1987-10-21 | — | — | EP | disclosed |